To make this Eggnog Crumb Cake Recipe gluten free, replace the all-purpose flour in both the crumb topping and cake batter with a certified gluten-free 1:1 baking flour blend. Verify that the eggnog, baking powder, baking soda, powdered sugar, sprinkles, spices, vanilla extract, and all packaged ingredients are labeled gluten free or free from gluten-containing additives. Use clean mixing bowls, measuring cups, utensils, and a clean baking pan to prevent cross-contact with gluten-containing ingredients.