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Golden baked biscuits served over creamy chicken with peas and vegetables on a plate.

Creamed Chicken and Biscuits Casserole

A comforting Creamed Chicken and Biscuits Casserole made with tender chicken, mixed vegetables, and a rich cream sauce, finished with fluffy baked biscuits for a hearty, family-style dinner.
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Course: Dinner, Main Course
Cuisine: American, Comfort Food
Keyword: Creamed Chicken and Biscuits Casserole
Prep Time: 10 minutes
Cook Time: 25 minutes
Total Time: 35 minutes
Servings: 6

Ingredients

  • 1 can 10.5 oz cream of potato soup
  • 1 can 10.5 oz cream of chicken soup
  • 1 cup milk
  • ½ teaspoon dried thyme
  • ½ teaspoon dried poultry seasoning
  • ¼ teaspoon ground black pepper
  • 1 bag 12 oz mixed frozen vegetables thawed and well drained
  • 4 cups cooked chicken cut into bite-sized pieces
  • 2 cans 12 oz each refrigerated biscuits cut into quarters Note: Approximately 1½ cans are typically sufficient

Instructions

  • Preheat the oven to 350°F (177°C). Lightly grease a 9 × 13-inch baking dish with nonstick cooking spray and set aside.
  • In a large mixing bowl, whisk together the cream of potato soup, cream of chicken soup, milk, dried thyme, poultry seasoning, and black pepper until the mixture is smooth and well combined.
  • Add the thawed and well-drained mixed vegetables and the cooked chicken to the bowl. Stir gently until all ingredients are evenly coated with the cream sauce.
  • Transfer the mixture to the prepared baking dish, spreading it evenly across the bottom.
  • Arrange the quartered biscuit pieces evenly over the top of the casserole.
  • Bake uncovered for 25–30 minutes, or until the casserole is bubbling and the biscuits are fully cooked through. To check for doneness, gently lift a biscuit from the center and ensure the bottom is no longer doughy.
  • If the casserole is fully heated but the biscuits require additional browning, place the dish under the broiler for 2–3 minutes, watching closely to prevent burning.
  • If the biscuits are sufficiently browned before the casserole is fully cooked, loosely tent the dish with aluminum foil and continue baking until the filling is hot and bubbly.

Notes

To prepare this dish gluten free, use certified gluten-free cream of chicken soup and cream of potato soup. Replace the refrigerated biscuits with a gluten-free biscuit dough or serve the casserole filling topped with gluten-free drop biscuits baked separately. Always verify that seasonings and frozen vegetables are labeled gluten free.