To make this recipe gluten free, replace the all-purpose flour with a certified gluten-free all-purpose flour blend suitable for thickening sauces. Also use certified gluten-free French fried onions, as traditional versions often contain wheat. Confirm that the sour cream, shredded cheese, seasonings, and frozen vegetable blends are gluten free, since some packaged products may contain additives or anti-caking ingredients with hidden gluten. If cross-contact is a concern, prepare the casserole using clean cookware and utensils and verify all labels carefully before use.